Clofibric acid

Clofibric acid is a herbicide with the IUPAC name 2-(4-chlorophenoxy)-2-methylpropanoic acid and molecular formula C10H11ClO3. It functions as a plant growth regulator against the plant hormone auxin. Clofibric acid is also a naturally-occurring pharmaceutical compound,[1] having been found in Swiss lakes and the North Sea.[2]

Clofibric acid
Names
Preferred IUPAC name
2-(4-Chlorophenoxy)-2-methylpropanoic acid
Other names
Clofibrin
Chlorofibrinic acid
Chlorophenoxyisobutyric acid
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.011.751
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
Properties
Chemical formula
 C10H11ClO3
Molar mass 214.645 g/mol
Appearance White to yellow solid
Melting point 118 to 123 °C (244 to 253 °F; 391 to 396 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Clofibric acid is a metabolite of the cholesterol-lowering pharmaceutical drug clofibrate, as well as that of the lipid regulators clofibrate, etofibrate, and theofibrate.[1]

Clofibric acid derivatives include etofibrate, pirifibrate, and picafibrate.

See also
  • Mecoprop

References
  1. Packer, Jennifer L; Werner, Jeffrey J; Latch, Douglas E; McNeill, Kristopher; Arnold, William A (2003). "Photochemical fate of pharmaceuticals in the environment: Naproxen, diclofenac, clofibric acid, and ibuprofen". Aquatic Sciences - Research Across Boundaries. 65 (4): 342–351. doi:10.1007/s00027-003-0671-8.
  2. Buser, Hans-Rudolf; Müller, Markus D; Theobald, Norbert (1998). "Occurrence of the Pharmaceutical Drug Clofibric Acid and the Herbicide Mecoprop in Various Swiss Lakes and in the North Sea". Environmental Science & Technology. 32: 188–192. doi:10.1021/es9705811.


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