Acedoben

Acedoben^[1]^[2]
	Skeletal formula
	Ball-and-stick model
Names
	Preferred IUPAC name 4-Acetamidobenzoic acid
	Other names N-Acetyl-PABA; 4-Carboxyacetanilide; p-Acetamidobenzoic acid p-Acetaminobenzoic acid; PAAB; p-Acetoaminobenzoic acid
Identifiers
CAS Number	556-08-1 ;
3D model (JSmol)	Interactive image; Interactive image; Interactive image;
ChEMBL	ChEMBL112687 ;
ChemSpider	18177 ;
DrugBank	DB04500 ;
ECHA InfoCard	100.008.287
PubChem CID	19266;
UNII	04Z20NMK31 ;
CompTox Dashboard (EPA)	DTXSID5024392 ;
	InChI InChI=1S/C9H9NO3/c1-6(11)10-8-4-2-7(3-5-8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13) Key: QCXJEYYXVJIFCE-UHFFFAOYSA-N ; InChI=1/C9H9NO3/c1-6(11)10-8-4-2-7(3-5-8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13) Key: QCXJEYYXVJIFCE-UHFFFAOYAT; InChI=1S/C9H9NO3/c1-6(11)10-8-4-2-7(3-5-8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13) Key: QCXJEYYXVJIFCE-UHFFFAOYSA-N;
	SMILES O=C(Nc1ccc(cc1)C(=O)O)C; O=C(Nc1ccc(cc1)C(=O)O)C; CC(=O)NC1=CC=C(C=C1)C(=O)O;
Properties
Chemical formula	C9H9NO3
Molar mass	179.175 g·mol−1
Melting point	259 to 262 °C (498 to 504 °F; 532 to 535 K) (dec.)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Acedoben (4-acetamidobenzoic acid or N-acetyl-PABA) is a chemical compound with the molecular formula of C₉H₉NO₃. It is the acetyl derivative of para-aminobenzoic acid (PABA).

Acedoben, as a salt with dimepranol, is a component of some pharmaceutical preparations such as inosine pranobex.

Acedoben has application in the synthesis of a drug that is called Tacedinaline.^[3]

References

^ "4-Acetamidobenzoic acid". Sigma-Aldrich.
^ Acedoben, ChemIndustry.com
^ Gediya, L. K.; Belosay, A.; Khandelwal, A.; Purushottamachar, P.; Njar, V. C. O. (March 2008). "Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts". Bioorganic & Medicinal Chemistry. 16 (6): 3352–3360. doi:10.1016/j.bmc.2007.12.007.

[1] "4-Acetamidobenzoic acid". Sigma-Aldrich.

[2] Acedoben, ChemIndustry.com

[3] Gediya, L. K.; Belosay, A.; Khandelwal, A.; Purushottamachar, P.; Njar, V. C. O. (March 2008). "Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts". Bioorganic & Medicinal Chemistry. 16 (6): 3352–3360. doi:10.1016/j.bmc.2007.12.007.

[1]

[2]

[3]

See also

References