Phosalone

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration on December 2006.

Phosalone
Names
IUPAC name
6-chloro-3-(diethoxyphosphinothioylsulfanylmethyl)-1,3-benzoxazol-2-one
Other names
Zolone
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.017.270
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
Properties
Chemical formula
 C12H15ClNO4PS2
Molar mass 367.80 g·mol−1
Appearance Colorless crystaline
Odor garlic
Density 1.39 g cm−3
Melting point 47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K)
Solubility in water
 3.05 mg/L
Solubility many organic solvents
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.[1]。It is a weak acetylcholinesterase inhibitor.[2] It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.[3] It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.[2] It is harmful especially to water creatures.

References
  1. 製品安全データシート（安全衛生情報センター） Archived 2014-10-25 at the Wayback Machine
  2. "国際化学物質安全性カード". Archived from the original on 2012-12-11. Retrieved 2012-09-06.
  3. 植村振作・河村宏・辻万千子・冨田重行・前田静夫著 (2002). 農薬毒性の事典 改訂版. 三省堂. ISBN 978-4385356044.
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