Metocurine |
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(1β)-6,6',7',12'-tetramethoxy-2,2,2',2'-tetramethyltubocuraran-2,2'-diium
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| Formula | C40H48N2O6 |
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| Molar mass | 652.832 g·mol−1 |
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| 3D model (JSmol) | |
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C[N+]1(CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C6[C@@H](CC7=CC(=C(C=C7)OC)O3)[N+](CCC6=CC(=C5OC)OC)(C)C)OC)C
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Metocurine is a muscle relaxant through neuromuscular blockade.[1]
It is excreted entirely through the kidneys and therefore should not be used in patients with kidney failure.
References
Skeletal muscle relaxants (M03) |
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Peripherally acting (primarily antinicotinic, NMJ block) | | Non-depolarizing | | Curare alkaloids |
- Alcuronium
- Dimethyltubocurarine
- Tubocurarine
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| 4° ammonium agents |
- ultra-short duration: Gantacurium
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| Depolarizing | |
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| ACh release inhibitors | |
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| Centrally acting | |
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| Directly acting | |
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Nicotinic acetylcholine receptor modulators |
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| nAChRsTooltip Nicotinic acetylcholine receptors | Agonists (and PAMsTooltip positive allosteric modulators) |
- 5-HIAA
- 6-Chloronicotine
- A-84,543
- A-366,833
- A-582,941
- A-867,744
- ABT-202
- ABT-418
- ABT-560
- ABT-894
- Acetylcholine
- Altinicline
- Anabasine
- Anatabine
- Anatoxin-a
- AR-R17779
- Bephenium hydroxynaphthoate
- Butinoline
- Butyrylcholine
- Carbachol
- Choline
- Choline m-bromophenyl ether
- Cotinine
- Cytisine
- Decamethonium
- Desformylflustrabromine
- Dianicline
- Dimethylphenylpiperazinium
- Epibatidine
- Epiboxidine
- Ethanol (alcohol)
- Ethoxysebacylcholine
- EVP-4473
- EVP-6124
- Galantamine
- GTS-21
- Ispronicline
- Ivermectin
- JNJ-39393406
- Levamisole
- Lobeline
- MEM-63,908 (RG-3487)
- Morantel
- Nicotine (tobacco)
- NS-1738
- PHA-543,613
- PHA-709,829
- PNU-120,596
- PNU-282,987
- Pozanicline
- Pyrantel
- Rivanicline
- RJR-2429
- Sazetidine A
- SB-206553
- Sebacylcholine
- SIB-1508Y
- SIB-1553A
- SSR-180,711
- Suberyldicholine
- Suxamethonium (succinylcholine)
- Suxethonium (succinyldicholine)
- TC-1698
- TC-1734
- TC-1827
- TC-2216
- TC-5214
- TC-5619
- TC-6683
- Tebanicline
- Tribendimidine
- Tropisetron
- UB-165
- Varenicline
- WAY-317,538
- XY-4083
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Antagonists (and NAMsTooltip negative allosteric modulators) | |
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Precursors (and prodrugs) | |
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- See also
- Receptor/signaling modulators
- Muscarinic acetylcholine receptor modulators
- Acetylcholine metabolism/transport modulators
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