Dibromochlorofluoromethane

Dibromochlorofluoromethane
Names
	Preferred IUPAC name Dibromo(chloro)fluoromethane
	Other names Dibromo-chloro-fluoromethane; Chlorodibromofluoromethane;
Identifiers
CAS Number	353-55-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	61027;
ECHA InfoCard	100.209.965
EC Number	684-518-8;
PubChem CID	67708;
UNII	70HAL49YC6;
CompTox Dashboard (EPA)	DTXSID70188809;
	InChI InChI=1S/CBr2ClF/c2-1(3,4)5 Key: HEDKQVNHJZBFQR-UHFFFAOYSA-N;
	SMILES C(F)(Cl)(Br)Br;
Properties
Chemical formula	CBr2ClF
Molar mass	226.27 g·mol−1
Density	2.6 g/cm3
Boiling point	78.9 °C (174.0 °F; 352.0 K)
Hazards
Flash point	1.5±18.4 °C
Related compounds
Related compounds	Bromochlorodifluoromethane; Bromodichlorofluoromethane; Bromochlorofluoromethane; Bromofluoroiodomethane; Bromodifluoroiodomethane; Bromofluorodiiodomethane; Chlorofluoroiodomethane; Chlorodifluoroiodomethane; Chlorofluorodiiodomethane;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Dibromochlorofluoromethane is a tetrahalomethane with the chemical formula CBr₂ClF.^[1]^[2] This is an organic compound containing two bromine atoms, one fluorine atom, and one chlorine atom attached to the methane backbone.^[3]^[4]

Synthesis

It can be prepared by reacting silver chlorobromoacetate with bromine at 180-260 °C, or by brominating fluorodichloromethane at 650 °C.^[5]

CBrClFCO₂Ag + Br₂ → CBr₂ClF + CO₂ + AgBr

Uses

It can be used to introduce chlorofluoromethyl groups into organic compounds.^[6]

References

^ Lide, David R. (9 March 1995). CRC Handbook of Chemistry and Physics: A Ready-reference Book of Chemical and Physical Data. CRC Press. p. 3-157. ISBN 978-0-8493-0595-5. Retrieved 8 September 2025.
^ "NCATS Inxight Drugs — DIBROMOCHLOROFLUOROMETHANE". drugs.ncats.io. Retrieved 8 September 2025.
^ "Dibromochlorofluoromethane". NIST. Retrieved 8 September 2025.
^ Luo, Yu-Ran (9 March 2007). Comprehensive Handbook of Chemical Bond Energies. CRC Press. p. 234. ISBN 978-1-4200-0728-2. Retrieved 8 September 2025.
^ Katritzky, Alan R.; Gilchrist, Thomas L.; Meth-Cohn, Otto; Rees, Charles Wayne (21 March 2003). Comprehensive Organic Functional Group Transformations. Elsevier. p. 225. ISBN 978-0-08-042704-1. Retrieved 8 September 2025.
^ Kvíčala, Jaroslav; Štambaský, Jan; Skalický, Martin; Paleta, Oldřich (1 October 2005). "Preparation of fluorohalomethylmagnesium halides using highly active magnesium metal and their reactions". Journal of Fluorine Chemistry. 126 (9): 1390–1395. Bibcode:2005JFluC.126.1390K. doi:10.1016/j.jfluchem.2005.07.016. ISSN 0022-1139. Retrieved 8 September 2025.

[1] Lide, David R. (9 March 1995). CRC Handbook of Chemistry and Physics: A Ready-reference Book of Chemical and Physical Data. CRC Press. p. 3-157. ISBN 978-0-8493-0595-5. Retrieved 8 September 2025.

[2] "NCATS Inxight Drugs — DIBROMOCHLOROFLUOROMETHANE". drugs.ncats.io. Retrieved 8 September 2025.

[3] "Dibromochlorofluoromethane". NIST. Retrieved 8 September 2025.

[4] Luo, Yu-Ran (9 March 2007). Comprehensive Handbook of Chemical Bond Energies. CRC Press. p. 234. ISBN 978-1-4200-0728-2. Retrieved 8 September 2025.

[5] Katritzky, Alan R.; Gilchrist, Thomas L.; Meth-Cohn, Otto; Rees, Charles Wayne (21 March 2003). Comprehensive Organic Functional Group Transformations. Elsevier. p. 225. ISBN 978-0-08-042704-1. Retrieved 8 September 2025.

[6] Kvíčala, Jaroslav; Štambaský, Jan; Skalický, Martin; Paleta, Oldřich (1 October 2005). "Preparation of fluorohalomethylmagnesium halides using highly active magnesium metal and their reactions". Journal of Fluorine Chemistry. 126 (9): 1390–1395. Bibcode:2005JFluC.126.1390K. doi:10.1016/j.jfluchem.2005.07.016. ISSN 0022-1139. Retrieved 8 September 2025.

[1]

[2]

[3]

[4]

[5]

[6]