Felbinac

Felbinac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical
ATC code
Legal status
Legal status
  • UK: P (Pharmacy medicines)
Identifiers
IUPAC name
  • biphenyl-4-ylacetic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.024.758
Chemical and physical data
FormulaC14H12O2
Molar mass212.248 g·mol−1
3D model (JSmol)
SMILES
  • O=C(O)Cc1ccc(cc1)c2ccccc2
InChI
  • InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) checkY
  • Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N checkY
  (verify)

Felbinac (INN, or biphenylylacetic acid) is a topical medicine,[1] belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis.[2] It is an active metabolite of fenbufen.[3]

The α-methyl acid of felbinac is called biprofen and is used to prepare bifepramide. The α-ethyl acid is called xenbucin which is used to make xenthiorate.

See also

References

  1. ^ The Merck Index, 12th Edition. 3989
  2. ^ Description of Felbinac on Tiscali [1]
  3. ^ Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.


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