Pyridinylpiperazine

Pyridinylpiperazine
Names
Preferred IUPAC name
1-(Pyridin-2-yl)piperazine
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.047.458
EC Number
  • 252-220-3
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2 checkY
    Key: GZRKXKUVVPSREJ-UHFFFAOYSA-N checkY
  • InChI=1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2
  • InChI=1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2
    Key: GZRKXKUVVPSREJ-UHFFFAOYSA-N
SMILES
  • n1ccccc1N2CCNCC2
Properties
Chemical formula
 C9H13N3
Molar mass 163.22 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

1-(2-Pyridinyl)piperazine is a chemical compound and piperazine derivative. Some derivatives of this substance are known to act as potent and selective α2-adrenergic receptor antagonists, such as 1-(3-fluoro-2-pyridinyl)piperazine.[1]

A few pyridinylpiperazine derivatives are drugs, including:

  • Azaperone — antipsychotic
  • Atevirdine — antiretroviral
  • Delavirdine — antiretroviral
  • Mirtazapine — antidepressant

See also

References

  1. ^ Saari WS, Halczenko W, King SW, et al. (December 1983). "Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists". Journal of Medicinal Chemistry. 26 (12): 1696–701. doi:10.1021/jm00366a007. PMID 6139479.
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